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Correlation between β-catenin mutations and expression of Wnt-signaling target genes in hepatocellular carcinoma
Aberrant Wnt-signaling caused by mutants of β-catenin, a key regulator of the canonical Wnt-signaling pathway, is frequently detected in cancer. Only recently, it was suggested that in hepatocellular carcinoma (HCC) the expression of the target gene glutamine synthetase (GS) is a highly reliable mar...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2287186/ https://www.ncbi.nlm.nih.gov/pubmed/18282277 http://dx.doi.org/10.1186/1476-4598-7-21 |