Nuclear envelope defects cause stem cell dysfunction in premature-aging mice

Nuclear lamina alterations occur in physiological aging and in premature aging syndromes. Because aging is also associated with abnormal stem cell homeostasis, we hypothesize that nuclear envelope alterations could have an important impact on stem cell compartments. To evaluate this hypothesis, we e...

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Detalles Bibliográficos
Autores principales: Espada, Jesús, Varela, Ignacio, Flores, Ignacio, Ugalde, Alejandro P., Cadiñanos, Juan, Pendás, Alberto M., Stewart, Colin L., Tryggvason, Karl, Blasco, María A., Freije, José M.P., López-Otín, Carlos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2287278/
https://www.ncbi.nlm.nih.gov/pubmed/18378773
http://dx.doi.org/10.1083/jcb.200801096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2287278/
https://www.ncbi.nlm.nih.gov/pubmed/18378773
http://dx.doi.org/10.1083/jcb.200801096

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