Compensatory role for Pyk2 during angiogenesis in adult mice lacking endothelial cell FAK

Focal adhesion kinase (FAK) plays a critical role during vascular development because knockout of FAK in endothelial cells (ECs) is embryonic lethal. Surprisingly, tamoxifen-inducible conditional knockout of FAK in adult blood vessels (inducible EC–specific FAK knockout [i-EC-FAK-KO]) produces no va...

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Detalles Bibliográficos
Autores principales: Weis, Sara M., Lim, Ssang-Taek, Lutu-Fuga, Kimberly M., Barnes, Leo A., Chen, Xiao Lei, Göthert, Joachim R., Shen, Tang-Long, Guan, Jun-Lin, Schlaepfer, David D., Cheresh, David A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2287283/
https://www.ncbi.nlm.nih.gov/pubmed/18391070
http://dx.doi.org/10.1083/jcb.200710038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2287283/
https://www.ncbi.nlm.nih.gov/pubmed/18391070
http://dx.doi.org/10.1083/jcb.200710038

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