Increased mitochondrial DNA damage and down-regulation of DNA repair enzymes in aged rodent retinal pigment epithelium and choroid

PURPOSE: In the central nervous system (CNS), increased mitochondrial DNA (mtDNA) damage is associated with aging and may underlie, contribute to, or increase the susceptibility to neurodegenerative diseases. Because of the focus on the retinal pigment epithelium (RPE) and choroid as tissue relevant...

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Detalles Bibliográficos
Autores principales: Wang, Ai Ling, Lukas, Thomas J., Yuan, Ming, Neufeld, Arthur H.
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2288587/
https://www.ncbi.nlm.nih.gov/pubmed/18392142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2288587/
https://www.ncbi.nlm.nih.gov/pubmed/18392142

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