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Darwinian Evolution on a Chip

Computer control of Darwinian evolution has been demonstrated by propagating a population of RNA enzymes in a microfluidic device. The RNA population was challenged to catalyze the ligation of an oligonucleotide substrate under conditions of progressively lower substrate concentrations. A microchip-...

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Detalles Bibliográficos
Autores principales: Paegel, Brian M, Joyce, Gerald F
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2288630/
https://www.ncbi.nlm.nih.gov/pubmed/18399721
http://dx.doi.org/10.1371/journal.pbio.0060085