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Darwinian Evolution on a Chip
Computer control of Darwinian evolution has been demonstrated by propagating a population of RNA enzymes in a microfluidic device. The RNA population was challenged to catalyze the ligation of an oligonucleotide substrate under conditions of progressively lower substrate concentrations. A microchip-...
Autores principales: | Paegel, Brian M, Joyce, Gerald F |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2288630/ https://www.ncbi.nlm.nih.gov/pubmed/18399721 http://dx.doi.org/10.1371/journal.pbio.0060085 |
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