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Sialoadhesin Expressed on IFN-Induced Monocytes Binds HIV-1 and Enhances Infectivity

BACKGROUND: HIV-1 infection dysregulates the immune system and alters gene expression in circulating monocytes. Differential gene expression analysis of CD14(+) monocytes from subjects infected with HIV-1 revealed increased expression of sialoadhesin (Sn, CD169, Siglec 1), a cell adhesion molecule f...

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Detalles Bibliográficos
Autores principales: Rempel, Hans, Calosing, Cyrus, Sun, Bing, Pulliam, Lynn
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2288672/
https://www.ncbi.nlm.nih.gov/pubmed/18414664
http://dx.doi.org/10.1371/journal.pone.0001967