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A P-glycoprotein homologue of Plasmodium falciparum is localized on the digestive vacuole
Resistance to chloroquine in Plasmodium falciparum bears a striking similarity to the multi-drug resistance (MDR) phenotype of mammalian tumor cells which is mediated by overexpression of P-glycoprotein. We show here that the P. falciparum homologue of the P-glycoprotein (Pgh1) is a 160,000-D protei...
| Formato: | Texto |
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| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1991
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2289011/ https://www.ncbi.nlm.nih.gov/pubmed/1674943 |