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Mechanism of cholera toxin action on a polarized human intestinal epithelial cell line: role of vesicular traffic
The massive secretion of salt and water in cholera-induced diarrhea involves binding of cholera toxin (CT) to ganglioside GM1 in the apical membrane of intestinal epithelial cells, translocation of the enzymatically active A1-peptide across the membrane, and subsequent activation of adenylate cyclas...
| Formato: | Texto |
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| Lenguaje: | English |
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The Rockefeller University Press
1992
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2289494/ https://www.ncbi.nlm.nih.gov/pubmed/1318883 |