SNP selection for genes of iron metabolism in a study of genetic modifiers of hemochromatosis

BACKGROUND: We report our experience of selecting tag SNPs in 35 genes involved in iron metabolism in a cohort study seeking to discover genetic modifiers of hereditary hemochromatosis. METHODS: We combined our own and publicly available resequencing data with HapMap to maximise our coverage to sele...

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Detalles Bibliográficos
Autores principales: Constantine, Clare C, Gurrin, Lyle C, McLaren, Christine E, Bahlo, Melanie, Anderson, Gregory J, Vulpe, Chris D, Forrest, Susan M, Allen, Katrina J, Gertig, Dorota M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2289803/
https://www.ncbi.nlm.nih.gov/pubmed/18366708
http://dx.doi.org/10.1186/1471-2350-9-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2289803/
https://www.ncbi.nlm.nih.gov/pubmed/18366708
http://dx.doi.org/10.1186/1471-2350-9-18

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