Binding mode prediction of conformationally restricted anandamide analogs within the CB(1 )receptor

BACKGROUND: CB(1 )cannabinoid receptors are G-protein coupled receptors for endocannabinoids including anandamide and 2-arachidonoylglycerol. Because these arachidonic acid metabolites possess a 20-carbon polyene chain as the alkyl terminal moiety, they are highly flexible with the potential to adop...

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Detalles Bibliográficos
Autores principales: Padgett, Lea W, Howlett, Allyn C, Shim, Joong-Youn
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2289822/
https://www.ncbi.nlm.nih.gov/pubmed/18302793
http://dx.doi.org/10.1186/1750-2187-3-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2289822/
https://www.ncbi.nlm.nih.gov/pubmed/18302793
http://dx.doi.org/10.1186/1750-2187-3-5

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