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Aminopeptidase N (APN)/CD13 inhibitor, Ubenimex, enhances radiation sensitivity in human cervical cancer

BACKGROUND: Radiotherapy can be used to treat all stages of cervical cancer. For improving local control via radiotherapy, it is important to use additional antitumor agents. Aminopeptidase N (APN)/CD13, a 150-kDa metalloproteinase, is a multifunctional cell surface aminopeptidase with ubiquitous ex...

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Detalles Bibliográficos
Autores principales: Tsukamoto, Hirohisa, Shibata, Kiyosumi, Kajiyama, Hiroaki, Terauchi, Mikio, Nawa, Akihiro, Kikkawa, Fumitaka
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2289833/
https://www.ncbi.nlm.nih.gov/pubmed/18366676
http://dx.doi.org/10.1186/1471-2407-8-74