High-Resolution Labeling and Functional Manipulation of Specific Neuron Types in Mouse Brain by Cre-Activated Viral Gene Expression

We describe a method that combines Cre-recombinase knockin mice and viral-mediated gene transfer to genetically label and functionally manipulate specific neuron types in the mouse brain. We engineered adeno-associated viruses (AAVs) that express GFP, dsRedExpress, or channelrhodopsin (ChR2) upon Cr...

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Detalles Bibliográficos
Autores principales: Kuhlman, Sandra J., Huang, Z. Josh
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2289876/
https://www.ncbi.nlm.nih.gov/pubmed/18414675
http://dx.doi.org/10.1371/journal.pone.0002005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2289876/
https://www.ncbi.nlm.nih.gov/pubmed/18414675
http://dx.doi.org/10.1371/journal.pone.0002005

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