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Thrombin receptor activation causes rapid neural cell rounding and neurite retraction independent of classic second messengers
The protease thrombin is a potent activator of various cell types. Thrombin cleaves and thereby activates its own seven-transmembrane- domain receptor which couples to G proteins. Thrombin also can inhibit neuronal differentiation, supposedly by degrading components of the extracellular matrix. Here...
Formato: | Texto |
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Lenguaje: | English |
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The Rockefeller University Press
1992
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2290045/ https://www.ncbi.nlm.nih.gov/pubmed/1321160 |