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Orchestration of the S-phase and DNA damage checkpoint pathways by replication forks from early origins

The S-phase checkpoint activated at replication forks coordinates DNA replication when forks stall because of DNA damage or low deoxyribonucleotide triphosphate pools. We explore the involvement of replication forks in coordinating the S-phase checkpoint using dun1Δ cells that have a defect in the n...

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Detalles Bibliográficos
Autores principales: Caldwell, Julie M., Chen, Yinhuai, Schollaert, Kaila L., Theis, James F., Babcock, George F., Newlon, Carol S., Sanchez, Yolanda
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2290838/
https://www.ncbi.nlm.nih.gov/pubmed/18347065
http://dx.doi.org/10.1083/jcb.200706009