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Shuttling of the chaperones Unc45b and Hsp90a between the A band and the Z line of the myofibril

The formation of thick filaments in striated muscle involves the chaperones Hsp90a and Unc45. We show that Unc45b and Hsp90a, two zebrafish orthologues, colocalize with myosin during myofibrillogenesis and associate with the Z line when myofibril assembly is completed. In response to stress or damag...

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Detalles Bibliográficos
Autores principales: Etard, Christelle, Roostalu, Urmas, Strähle, Uwe
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2290844/
https://www.ncbi.nlm.nih.gov/pubmed/18347070
http://dx.doi.org/10.1083/jcb.200709128