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A systems-level approach to mapping the telomere length maintenance gene circuitry

The ends of eukaryotic chromosomes are protected by telomeres, nucleoprotein structures that are essential for chromosomal stability and integrity. Understanding how telomere length is controlled has significant medical implications, especially in the fields of aging and cancer. Two recent systemati...

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Detalles Bibliográficos
Autores principales: Shachar, Rafi, Ungar, Lior, Kupiec, Martin, Ruppin, Eytan, Sharan, Roded
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2290934/
https://www.ncbi.nlm.nih.gov/pubmed/18319724
http://dx.doi.org/10.1038/msb.2008.13