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A comprehensive modular map of molecular interactions in RB/E2F pathway

We present, here, a detailed and curated map of molecular interactions taking place in the regulation of the cell cycle by the retinoblastoma protein (RB/RB1). Deregulations and/or mutations in this pathway are observed in most human cancers. The map was created using Systems Biology Graphical Notat...

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Detalles Bibliográficos
Autores principales: Calzone, Laurence, Gelay, Amélie, Zinovyev, Andrei, Radvanyi, François, Barillot, Emmanuel
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2290939/
https://www.ncbi.nlm.nih.gov/pubmed/18319725
http://dx.doi.org/10.1038/msb.2008.7