Cargando…

The liver pharmacological and xenobiotic gene response repertoire

We have used a supervised classification approach to systematically mine a large microarray database derived from livers of compound-treated rats. Thirty-four distinct signatures (classifiers) for pharmacological and toxicological end points can be identified. Just 200 genes are sufficient to classi...

Descripción completa

Detalles Bibliográficos
Autores principales: Natsoulis, Georges, Pearson, Cecelia I, Gollub, Jeremy, P Eynon, Barrett, Ferng, Joe, Nair, Ramesh, Idury, Radha, Lee, May D, Fielden, Mark R, Brennan, Richard J, Roter, Alan H, Jarnagin, Kurt
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2290941/
https://www.ncbi.nlm.nih.gov/pubmed/18364709
http://dx.doi.org/10.1038/msb.2008.9