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Use of Cell Viability Assay Data Improves the Prediction Accuracy of Conventional Quantitative Structure–Activity Relationship Models of Animal Carcinogenicity

BACKGROUND: To develop efficient approaches for rapid evaluation of chemical toxicity and human health risk of environmental compounds, the National Toxicology Program (NTP) in collaboration with the National Center for Chemical Genomics has initiated a project on high-throughput screening (HTS) of...

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Detalles Bibliográficos
Autores principales: Zhu, Hao, Rusyn, Ivan, Richard, Ann, Tropsha, Alexander
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2291015/
https://www.ncbi.nlm.nih.gov/pubmed/18414635
http://dx.doi.org/10.1289/ehp.10573