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Nuclear Factor-kappa B as a Resistance Factor to Platinum-Based Antineoplasic Drugs

Platinum drugs continue to be major chemotherapy drugs for cancer treatment. Nevertheless, acquired or intrinsic resistance to these compounds is common in human tumors. One important mechanism for this resistance is the avoidance of cells entering the apoptotic pathway. Nuclear factor-kappa B (NF-k...

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Detalles Bibliográficos
Autores principales: Lagunas, Vilma Maldonado, Meléndez-Zajgla, Jorge
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2291150/
https://www.ncbi.nlm.nih.gov/pubmed/18414584
http://dx.doi.org/10.1155/2008/576104