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IL-10 from CD4(+)CD25(−)Foxp3(−)CD127(−) Adaptive Regulatory T Cells Modulates Parasite Clearance and Pathology during Malaria Infection

The outcome of malaria infection is determined, in part, by the balance of pro-inflammatory and regulatory immune responses. Failure to develop an effective pro-inflammatory response can lead to unrestricted parasite replication, whilst failure to regulate this response leads to the development of s...

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Detalles Bibliográficos
Autores principales: Couper, Kevin N., Blount, Daniel G., Wilson, Mark S., Hafalla, Julius C., Belkaid, Yasmine, Kamanaka, Masahito, Flavell, Richard A., de Souza, J. Brian, Riley, Eleanor M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2291447/
https://www.ncbi.nlm.nih.gov/pubmed/18401464
http://dx.doi.org/10.1371/journal.ppat.1000004