Neuroinflammation mediated by IL-1β increases susceptibility of dopamine neurons to degeneration in an animal model of Parkinson's disease

BACKGROUND: The etiology of Parkinson's disease (PD) remains elusive despite identification of several genetic mutations. It is more likely that multiple factors converge to give rise to PD than any single cause. Here we report that inflammation can trigger degeneration of dopamine (DA) neurons...

Descripción completa

Detalles Bibliográficos
Autores principales: Koprich, James B, Reske-Nielsen, Casper, Mithal, Prabhakar, Isacson, Ole
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292163/
https://www.ncbi.nlm.nih.gov/pubmed/18304357
http://dx.doi.org/10.1186/1742-2094-5-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292163/
https://www.ncbi.nlm.nih.gov/pubmed/18304357
http://dx.doi.org/10.1186/1742-2094-5-8

Ejemplares similares