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Synthetic chemerin-derived peptides suppress inflammation through ChemR23

Chemerin is a chemotactic protein that binds to the G protein–coupled receptor, ChemR23. We demonstrate that murine chemerin possesses potent antiinflammatory properties that are absolutely dependent on proteolytic processing. A series of peptides was designed, and only those identical to specific C...

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Detalles Bibliográficos
Autores principales: Cash, Jenna L., Hart, Rosie, Russ, Andreas, Dixon, John P.C., Colledge, William H., Doran, Joanne, Hendrick, Alan G., Carlton, Mark B.L., Greaves, David R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292217/
https://www.ncbi.nlm.nih.gov/pubmed/18391062
http://dx.doi.org/10.1084/jem.20071601