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CXCR4 is required for the quiescence of primitive hematopoietic cells

The quiescence of hematopoietic stem cells (HSCs) is critical for preserving a lifelong steady pool of HSCs to sustain the highly regenerative hematopoietic system. It is thought that specialized niches in which HSCs reside control the balance between HSC quiescence and self-renewal, yet little is k...

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Detalles Bibliográficos
Autores principales: Nie, Yuchun, Han, Yoon-Chi, Zou, Yong-Rui
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292218/
https://www.ncbi.nlm.nih.gov/pubmed/18378795
http://dx.doi.org/10.1084/jem.20072513