Cargando…

Distinct cell-specific control of autoimmunity and infection by FcγRIIb

FcγRIIb is an inhibitory Fc receptor expressed on B cells and myeloid cells. It is important in controlling responses to infection, and reduced expression or function predisposes to autoimmunity. To determine if increased expression of FcγRIIb can modulate these processes, we created transgenic mice...

Descripción completa

Detalles Bibliográficos
Autores principales: Brownlie, Rebecca J., Lawlor, Kate E., Niederer, Heather A., Cutler, Antony J., Xiang, Zou, Clatworthy, Menna R., Floto, R. Andres, Greaves, David R., Lyons, Paul A., Smith, Kenneth G.C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292226/
https://www.ncbi.nlm.nih.gov/pubmed/18362174
http://dx.doi.org/10.1084/jem.20072565