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IL-9– and mast cell–mediated intestinal permeability predisposes to oral antigen hypersensitivity

Previous mouse and clinical studies demonstrate a link between Th2 intestinal inflammation and induction of the effector phase of food allergy. However, the mechanism by which sensitization and mast cell responses occurs is largely unknown. We demonstrate that interleukin (IL)-9 has an important rol...

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Detalles Bibliográficos
Autores principales: Forbes, Elizabeth E., Groschwitz, Katherine, Abonia, J. Pablo, Brandt, Eric B., Cohen, Elizabeth, Blanchard, Carine, Ahrens, Richard, Seidu, Luqman, McKenzie, Andrew, Strait, Richard, Finkelman, Fred D., Foster, Paul S., Matthaei, Klaus I., Rothenberg, Marc E., Hogan, Simon P.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292227/
https://www.ncbi.nlm.nih.gov/pubmed/18378796
http://dx.doi.org/10.1084/jem.20071046