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Gene placement and competition control T cell receptor γ variable region gene rearrangement
The production of distinct sets of T cell receptor (TCR) γδ(+) T cells occurs in an ordered fashion in thymic development. The Vγ3 and Vγ4 genes, located downstream in the TCRγ Cγ1 gene cluster, are expressed by the earliest waves of developing TCRγδ(+) T cells in the fetal thymus, destined for intr...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292229/ https://www.ncbi.nlm.nih.gov/pubmed/18378791 http://dx.doi.org/10.1084/jem.20071275 |