The orthopoxvirus type I IFN binding protein is essential for virulence and an effective target for vaccination

Nonliving antiviral vaccines traditionally target proteins expressed at the surface of the virion with the hope of inducing neutralizing antibodies. Orthopoxviruses (OPVs), such as the human smallpox virus and the mouse-equivalent ectromelia virus (ECTV; an agent of mousepox), encode immune response...

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Detalles Bibliográficos
Autores principales: Xu, Ren-Huan, Cohen, Matthew, Tang, Yong, Lazear, Eric, Whitbeck, J. Charles, Eisenberg, Roselyn J., Cohen, Gary H., Sigal, Luis J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292233/
https://www.ncbi.nlm.nih.gov/pubmed/18391063
http://dx.doi.org/10.1084/jem.20071854

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292233/
https://www.ncbi.nlm.nih.gov/pubmed/18391063
http://dx.doi.org/10.1084/jem.20071854

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