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Metabolic and Immune Activation Effects of Treatment Interruption in Chronic HIV-1 Infection: Implications for Cardiovascular Risk

BACKGROUND: Concern about costs and antiretroviral therapy (ART)-associated toxicities led to the consideration of CD4 driven strategies for the management of HIV. That approach was evaluated in the SMART trial that reported an unexpected increase of cardiovascular events after treatment interruptio...

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Detalles Bibliográficos
Autores principales: Tebas, Pablo, Henry, William Keith, Matining, Roy, Weng-Cherng, Deborah, Schmitz, John, Valdez, Hernan, Jahed, Nasreen, Myers, Laurie, Powderly, William G., Katzenstein, David
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292263/
https://www.ncbi.nlm.nih.gov/pubmed/18431498
http://dx.doi.org/10.1371/journal.pone.0002021