A Residue at the Cytoplasmic Entrance of BK-Type Channels Regulating Single-Channel Opening by Its Hydrophobicity

Single large-conductance calcium-activated K(+) (BK) channels encoded by the mSlo gene usually have synchronous gating, but a Drosophila dSlo (A2/C2/E2/G5/10) splice variant (dSlo1A) exhibits very flickery openings. To probe this difference in gating, we constructed a mutant I323T. This channel exhi...

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Detalles Bibliográficos
Autores principales: Guo, Zhaohua, Lv, Caixia, Yi, Hong, Xiong, Yu, Wu, Yingliang, Li, Wenxin, Xu, Tao, Ding, Jiuping
Formato: Texto
Lenguaje:English
Publicado: The Biophysical Society 2008
Materias:
Electrophysiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292367/
https://www.ncbi.nlm.nih.gov/pubmed/18400952
http://dx.doi.org/10.1529/biophysj.107.120022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292367/
https://www.ncbi.nlm.nih.gov/pubmed/18400952
http://dx.doi.org/10.1529/biophysj.107.120022

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