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In Vitro Performance Testing of the Novel Medspray® Wet Aerosol Inhaler Based on the Principle of Rayleigh Break-up

PURPOSE: A new inhaler (Medspray®) for pulmonary drug delivery based on the principle of Rayleigh break-up has been tested with three different spray nozzles (1.5; 2.0 and 2.5 μm) using aqueous 0.1% (w/w) salbutamol and 0.9% (w/w) sodium chloride solutions. MATERIALS AND METHODS: Particle size distr...

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Detalles Bibliográficos
Autores principales: de Boer, Anne H., Wissink, Jeroen, Hagedoorn, Paul, Heskamp, Iwan, de Kruijf, Wilbur, Bünder, Ralf, Zanen, Pieter, Munnik, Paul, van Rijn, Cees, Frijlink, Henderik W.
Formato: Texto
Lenguaje:English
Publicado: Springer US 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292500/
https://www.ncbi.nlm.nih.gov/pubmed/18066714
http://dx.doi.org/10.1007/s11095-007-9503-1