Src homology 2 (SH2) domain containing protein tyrosine phosphatase-1 (SHP-1) dephosphorylates VEGF Receptor-2 and attenuates endothelial DNA synthesis, but not migration*

BACKGROUND: Vascular endothelial growth factor receptor-2 (VEGFR-2, KDR), a receptor tyrosine kinase, regulates mitogenic, chemotactic, hyperpermeability, and survival signals in vascular endothelial cells in response to its ligand vascular permeability factor/ vascular endothelial growth factor (VP...

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Detalles Bibliográficos
Autores principales: Bhattacharya, Resham, Kwon, Junhye, Wang, Enfeng, Mukherjee, Priyabrata, Mukhopadhyay, Debabrata
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292718/
https://www.ncbi.nlm.nih.gov/pubmed/18377662
http://dx.doi.org/10.1186/1750-2187-3-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292718/
https://www.ncbi.nlm.nih.gov/pubmed/18377662
http://dx.doi.org/10.1186/1750-2187-3-8

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