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A new approach for the large-scale generation of mature dendritic cells from adherent PBMC using roller bottle technology

BACKGROUND: Human monocyte-derived DC (mDC) loaded with peptides, protein, tumor cell lysates, or tumor cell RNA, are being tested as vaccines against multiple human malignancies and viral infection with great promise. One of the factors that has limited more widespread use of these vaccines is the...

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Detalles Bibliográficos
Autores principales: Campbell-Anson, Ryan E, Kentor, Diane, Wang, Yi J, Bushnell, Kathryn M, Li, Yufeng, Vence, Luis M, Radvanyi, Laszlo G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292722/
https://www.ncbi.nlm.nih.gov/pubmed/18321390
http://dx.doi.org/10.1186/1476-8518-6-1