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Host PrP Glycosylation: A Major Factor Determining the Outcome of Prion Infection
The expression of the prion protein (PrP) is essential for transmissible spongiform encephalopathy (TSE) or prion diseases to occur, but the underlying mechanism of infection remains unresolved. To address the hypothesis that glycosylation of host PrP is a major factor influencing TSE infection, we...
Autores principales: | , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292751/ https://www.ncbi.nlm.nih.gov/pubmed/18416605 http://dx.doi.org/10.1371/journal.pbio.0060100 |