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Comprehensive transcriptional profiling of prion infection in mouse models reveals networks of responsive genes
BACKGROUND: Prion infection results in progressive neurodegeneration of the central nervous system invariably resulting in death. The pathological effects of prion diseases in the brain are morphologically well defined, such as gliosis, vacuolation, and the accumulation of disease-specific protease-...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2294129/ https://www.ncbi.nlm.nih.gov/pubmed/18315872 http://dx.doi.org/10.1186/1471-2164-9-114 |