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Comprehensive transcriptional profiling of prion infection in mouse models reveals networks of responsive genes

BACKGROUND: Prion infection results in progressive neurodegeneration of the central nervous system invariably resulting in death. The pathological effects of prion diseases in the brain are morphologically well defined, such as gliosis, vacuolation, and the accumulation of disease-specific protease-...

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Detalles Bibliográficos
Autores principales:	Sorensen, Garrett, Medina, Sarah, Parchaliuk, Debra, Phillipson, Clark, Robertson, Catherine, Booth, Stephanie A
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2294129/ https://www.ncbi.nlm.nih.gov/pubmed/18315872 http://dx.doi.org/10.1186/1471-2164-9-114

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