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Solution structure of the Legionella pneumophila Mip-rapamycin complex

BACKGROUND: Legionella pneumphila is the causative agent of Legionnaires' disease. A major virulence factor of the pathogen is the homodimeric surface protein Mip. It shows peptidyl-prolyl cis/trans isomerase activty and is a receptor of FK506 and rapamycin, which both inhibit its enzymatic fun...

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Detalles Bibliográficos
Autores principales: Ceymann, Andreas, Horstmann, Martin, Ehses, Philipp, Schweimer, Kristian, Paschke, Anne-Katrin, Steinert, Michael, Faber, Cornelius
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2311308/
https://www.ncbi.nlm.nih.gov/pubmed/18366641
http://dx.doi.org/10.1186/1472-6807-8-17