Utilization of a Deoxynucleoside Diphosphate Substrate by HIV Reverse Transcriptase

BACKGROUND: Deoxynucleoside triphosphates (dNTPs) are the normal substrates for DNA synthesis catalyzed by polymerases such as HIV-1 reverse transcriptase (RT). However, substantial amounts of deoxynucleoside diphosphates (dNDPs) are also present in the cell. Use of dNDPs in HIV-1 DNA synthesis coul...

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Detalles Bibliográficos
Autores principales: Garforth, Scott J., Parniak, Michael A., Prasad, Vinayaka R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2312326/
https://www.ncbi.nlm.nih.gov/pubmed/18446195
http://dx.doi.org/10.1371/journal.pone.0002074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2312326/
https://www.ncbi.nlm.nih.gov/pubmed/18446195
http://dx.doi.org/10.1371/journal.pone.0002074

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