Proofreading Activity of DNA Polymerase Pol2 Mediates 3′-End Processing during Nonhomologous End Joining in Yeast

Genotoxic agents that cause double-strand breaks (DSBs) often generate damage at the break termini. Processing enzymes, including nucleases and polymerases, must remove damaged bases and/or add new bases before completion of repair. Artemis is a nuclease involved in mammalian nonhomologous end joini...

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Detalles Bibliográficos
Autores principales: Tseng, Shun-Fu, Gabriel, Abram, Teng, Shu-Chun
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2312331/
https://www.ncbi.nlm.nih.gov/pubmed/18437220
http://dx.doi.org/10.1371/journal.pgen.1000060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2312331/
https://www.ncbi.nlm.nih.gov/pubmed/18437220
http://dx.doi.org/10.1371/journal.pgen.1000060

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