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Drug 9AA reactivates p21/Waf1 and Inhibits HIV-1 progeny formation

It has been demonstrated that the p53 pathway plays an important role in HIV-1 infection. Previous work from our lab has established a model demonstrating how p53 could become inactivated in HIV-1 infected cells through binding to Tat. Subsequently, p53 was inactivated and lost its ability to transa...

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Detalles Bibliográficos
Autores principales: Wu, Weilin, Kehn-Hall, Kylene, Pedati, Caitlin, Zweier, Lynnsey, Castro, Iris, Klase, Zachary, Dowd, Cynthia S, Dubrovsky, Larisa, Bukrinsky, Michael, Kashanchi, Fatah
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2315641/
https://www.ncbi.nlm.nih.gov/pubmed/18348731
http://dx.doi.org/10.1186/1743-422X-5-41