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Aurora B kinase and protein phosphatase 1 have opposing roles in modulating kinetochore assembly

The outer kinetochore binds microtubules to control chromosome movement. Outer kinetochore assembly is restricted to mitosis, whereas the inner kinetochore remains tethered to centromeres throughout the cell cycle. The cues that regulate this transient assembly are unknown. We find that inhibition o...

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Detalles Bibliográficos
Autores principales: Emanuele, Michael J., Lan, Weijie, Jwa, Miri, Miller, Stephanie A., Chan, Clarence S.M., Stukenberg, P. Todd
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2315672/
https://www.ncbi.nlm.nih.gov/pubmed/18426974
http://dx.doi.org/10.1083/jcb.200710019