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Aurora B kinase and protein phosphatase 1 have opposing roles in modulating kinetochore assembly
The outer kinetochore binds microtubules to control chromosome movement. Outer kinetochore assembly is restricted to mitosis, whereas the inner kinetochore remains tethered to centromeres throughout the cell cycle. The cues that regulate this transient assembly are unknown. We find that inhibition o...
Autores principales: | Emanuele, Michael J., Lan, Weijie, Jwa, Miri, Miller, Stephanie A., Chan, Clarence S.M., Stukenberg, P. Todd |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2315672/ https://www.ncbi.nlm.nih.gov/pubmed/18426974 http://dx.doi.org/10.1083/jcb.200710019 |
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