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The highly conserved nuclear lamin Ig-fold binds to PCNA: its role in DNA replication
This study provides insights into the role of nuclear lamins in DNA replication. Our data demonstrate that the Ig-fold motif located in the lamin C terminus binds directly to proliferating cell nuclear antigen (PCNA), the processivity factor necessary for the chain elongation phase of DNA replicatio...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2315674/ https://www.ncbi.nlm.nih.gov/pubmed/18426975 http://dx.doi.org/10.1083/jcb.200708155 |