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The highly conserved nuclear lamin Ig-fold binds to PCNA: its role in DNA replication

This study provides insights into the role of nuclear lamins in DNA replication. Our data demonstrate that the Ig-fold motif located in the lamin C terminus binds directly to proliferating cell nuclear antigen (PCNA), the processivity factor necessary for the chain elongation phase of DNA replicatio...

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Detalles Bibliográficos
Autores principales: Shumaker, Dale K., Solimando, Liliana, Sengupta, Kaushik, Shimi, Takeshi, Adam, Stephen A., Grunwald, Antje, Strelkov, Sergei V., Aebi, Ueli, Cardoso, M. Cristina, Goldman, Robert D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2315674/
https://www.ncbi.nlm.nih.gov/pubmed/18426975
http://dx.doi.org/10.1083/jcb.200708155