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A cell-based reglucosylation assay demonstrates the role of GT1 in the quality control of a maturing glycoprotein

The endoplasmic reticulum (ER) protein GT1 (UDP-glucose: glycoprotein glucosyltransferase) is the central enzyme that modifies N-linked carbohydrates based upon the properties of the polypeptide backbone of the maturing substrate. GT1 adds glucose residues to nonglucosylated proteins that fail the q...

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Detalles Bibliográficos
Autores principales: Pearse, Bradley R., Gabriel, Luke, Wang, Ning, Hebert, Daniel N.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2315677/
https://www.ncbi.nlm.nih.gov/pubmed/18426978
http://dx.doi.org/10.1083/jcb.200712068