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A cell-based reglucosylation assay demonstrates the role of GT1 in the quality control of a maturing glycoprotein
The endoplasmic reticulum (ER) protein GT1 (UDP-glucose: glycoprotein glucosyltransferase) is the central enzyme that modifies N-linked carbohydrates based upon the properties of the polypeptide backbone of the maturing substrate. GT1 adds glucose residues to nonglucosylated proteins that fail the q...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2315677/ https://www.ncbi.nlm.nih.gov/pubmed/18426978 http://dx.doi.org/10.1083/jcb.200712068 |