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Deletion of a xenobiotic metabolizing gene in mice affects folate metabolism

The mouse arylamine N-acetyltransferase 2 (Nat2) and its homologue (NAT1) in humans are known to detoxify xenobiotic arylamines and are also thought to play a role in endogenous metabolism. Human NAT1 is highly over-expressed in estrogen receptor positive breast tumours and is implicated in suscepti...

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Detalles Bibliográficos
Autores principales: Wakefield, Larissa, Cornish, Valerie, Long, Hilary, Griffiths, William J., Sim, Edith
Formato: Texto
Lenguaje:English
Publicado: Academic Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2315789/
https://www.ncbi.nlm.nih.gov/pubmed/17961509
http://dx.doi.org/10.1016/j.bbrc.2007.10.026