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A Coarse-Grained Biophysical Model of E. coli and Its Application to Perturbation of the rRNA Operon Copy Number

We propose a biophysical model of Escherichia coli that predicts growth rate and an effective cellular composition from an effective, coarse-grained representation of its genome. We assume that E. coli is in a state of balanced exponential steady-state growth, growing in a temporally and spatially c...

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Detalles Bibliográficos
Autores principales: Tadmor, Arbel D., Tlusty, Tsvi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2320978/
https://www.ncbi.nlm.nih.gov/pubmed/18437222
http://dx.doi.org/10.1371/journal.pcbi.1000038