SARS-Coronavirus Replication/Transcription Complexes Are Membrane-Protected and Need a Host Factor for Activity In Vitro

SARS-coronavirus (SARS-CoV) replication and transcription are mediated by a replication/transcription complex (RTC) of which virus-encoded, non-structural proteins (nsps) are the primary constituents. The 16 SARS-CoV nsps are produced by autoprocessing of two large precursor polyproteins. The RTC is...

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Detalles Bibliográficos
Autores principales: van Hemert, Martijn J., van den Worm, Sjoerd H. E., Knoops, Kèvin, Mommaas, A. Mieke, Gorbalenya, Alexander E., Snijder, Eric J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2322833/
https://www.ncbi.nlm.nih.gov/pubmed/18451981
http://dx.doi.org/10.1371/journal.ppat.1000054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2322833/
https://www.ncbi.nlm.nih.gov/pubmed/18451981
http://dx.doi.org/10.1371/journal.ppat.1000054

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