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Treatment of experimental colitis in mice with LMP-420, an inhibitor of TNF transcription
BACKGROUND: LMP-420 is a boronic acid-containing purine nucleoside analogue that transcriptionally inhibits TNF production but is non-cytotoxic to TNF-producing cells. METHODS: This study investigated the efficacy of LMP-420 as an anti-inflammatory agent in acute and chronic colitis induced by oral...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2322983/ https://www.ncbi.nlm.nih.gov/pubmed/18331642 http://dx.doi.org/10.1186/1476-9255-5-4 |